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- How do I apply for stem cell treatment in your hospital?
- What are neural stem cells?
- What kinds of diseases could be treated by stem cells?
- Where are the neural stem cells derived from?
- How many courses of treatment are needed for cerebellar atrophy?
- Are there any side effects for stem cell treatment?
- How much does stem cell treatment cost?
- Is Friedreich ataxia curable?
- What is the advantage of stem cell treatment over there?
- What is the success rate for Friedreich ataxia?
Q: What are neural stem cells?
A: Neural stem cells(NSCs) are considered a heterogenous population of mitotically active, self-renewing, multipotent, immature progenitor cells of both the developing and the adult nervous system showing complex atterns of gene expression that vary in space and time. They have the capacity to generate neurons, astrocytes and oligodentrocytes which constructed nervous system.
Q: What kinds of diseases could be treated with neural stem cell transplantation? Are the same NSCs used to the patients?
A: NSCs transplantation therapy could treat several central nervous disease(CND), including stroke, spinocerebellar ataxia(SCA), multiple system atrophy(MSA), multiple sclerosis, hereditary ataxia, spinal cord injury(SCI), cerebral palsy, parkinson's disease(PD) and amyotrophic lateral sclerosis(ALS). Moreover, NSCs could be used in the treatment of optic atrophy and sleep disorder in our hospital.
In fact, the NSCs used are not completely the same for different treatments. The NSCs used for transplantation are exclusively cultured according to the patients ages, weight, diseases, disease conditions as well as the other factors that are unique to a certain patient.
Q: How long will it need to culture NSCs?
A: About 5-7 days. So if the patients want to receive NSCs transplantation in our hospital, you need to make a pre-scheduled appointment to us(at least one week before you come to our hospital).
Q: The NSCs were cultured in what conditions? And how long can the cultured NSCs be stored?
A: NSCs were collected in a GMP lab. Thus the NSCs for transplantation will be avoided from microbial contamination and maintain their biological functions before transplantation. They are safe for transplantation therapy. According to our clinical experience, the NSCs can be injected to the patients within 10 hours after culture in vitro. For the sake of safety, we inject the NSCs into the patients within 4 hours after culture in vitro.
Q: Where are the NSCs derived in your hospital?
A: They are derived from cord blood, autologous bone marrow or embryos.
Q: What about the situation of neural stem cell therapy in China?
A: China is home to leading stem cell research and treatment hospitals that offer sufferers who want to take advantage of stem cell treatments that are still considered experimental or have yet to be approved in their home country.
In general, we have treated more than 1000 patients with neural stem cell with a coefficient of efficiency of 79.3% after transplantation. Among these, the coefficient of efficiency for spinal cord injury, stroke, cerebral atrophy,parkinson's disease and multiple system athophy treatment is 83.1% while it is 65.0% for the patients suffering from multiple sclerosis, hereditary ataxia, motor neuron disease and amyotrophic lateral sclerosis.
Q: How long will neural stem cell take effect after transplantation?
A: Neural stem cells will secrete several kinds of neurotrophic factors(NTFs) after transplantation, which plays an important role in nurturing the patients¡¯ nervous system. Neural stem cells reach the diseased region through cerebrospinal fluid circulation and their tropism. Then these stem cells differentiated into the neurocytes under the certain internal microenvironment. As the number of neurocytes reaches to a threshold, they will interact with the other cells to repair the diseased region. According to our clinical results, most of the patients showed better health conditions about 3 months after neural stem cell transplantation. In certain extreme situations, the patient showed better conditions at about 1 month after transplantation, and some have to wait at least 7 or 8 months before neural stem cell therapy takes effect(this depends on the patients¡¯ health conditions).
Q: How many courses of treatment are needed for NSC transplantation?
A: It is hard to speculate how many courses of treatment are needed for the patients as the disease conditions and NSCs treatment effectiveness are different among the patients. In most cases, 1 or 2 courses of treatment will be OK.
Q: What should I do if I want to receive NSC transplantation therapy in your hospital?
A: First, you need to upload your case at Online Inquiry Then we will give you the feedback. Second, you need to make an appointment to our hospital and pay the fee.Then you can receive neural stem cell treatment in our hospital.
Q: Are there any side effects for NSC transplantation therapy? Why?
A: The most common post surgery reactions of NSC transplantation include headache, dizzy, nausea, vomitting, low-grade fever, tremor, excitation and hiccough. According to our clinical experiences, these manifestations are normal, and only existed in rare cases. They will last for 1 to 3 days if possible(3 hours per day), and will disappear spontaneously. Furthermore, you don't need to care about oncogenicity of stem cell because we use NSC rather than embryonic stem cell for transplantation.
